O Γεώργιος Κ Αναγνωστόπουλος γεννήθηκε  στην Αθήνα στις 19/3/1970. Αποφοίτησε  το 1987 από το Πρότυπο Λύκειο  Αναβρύτων και το 1993 πήρε με  ‘άριστα’ το πτυχίο της ιατρικής  από την Ιατρική Σχολή του  Εθνικού και Καποδιστριακού Πανεπιστημίου  Αθηνών. Αφού εξέτισε την στρατιωτική  του θητεία στο Πολεμικό Ναυτικό  και το αγροτικό του στο  άγονο περιφερικό ιατρείο της  νήσου Ίου, ειδικεύθηκε στην  Γαστρεντερολογία στο 251 Γενικό Νοσοκομείο της Αεροπoρίας. Το 2002 έλαβε υποτροφία από την Ελληνική Γαστρεντερολογική Εταιρεία και μετεκπαιδεύθηκε στα Wolfson Digestive Diseases Centre, University of Nottingham UK ως Advanced Endoscopy Research Fellow και Endoscopy department, University of Mainz, Germany στις προηγμένες μικροενδοσκοπικές διαγνωστικές και θεραπευτικές τεχνικές [μεγεθυντική ενδοσκόπηση, χρωμοενδοσκόπηση, Νarrow Band Imaging, confocal endomicroscopy, autofluorescence endoscopy, ενδοσκοπική βλεννογονεκτομή, φωτοδυναμική θεραπεία σε οισοφάγο Barrett’s]. Χρησιμοποιεί την μέθοδο της υψηλής ευκρίνειας μεγεθυντικής χρωμοενδοσκόπησης που είναι ουσιαστικά επανάσταση στην πρόληψη, έγκαιρη διάγνωση και θεραπεία των προκαρκινικών καταστάσεων και του πρώιμου καρκίνου στο πεπτικό.

Στην  Ελλάδα εργάζεται στον ιδιωτικό τομέα από το 2007 ενώ παράλληλα συνεχίζει το ερευνητικό και κλινικό του έργο. Aπό το 2011 είναι Section Editor στο επίσημο περιοδικό της Ελληνικής Γαστρεντερολογικής Εταιρείας [Αnnals of Gastroenterology], και έχει εκλεγεί μέλος του Ενδοσκοπικού τμήματος της Γαστρεντερολογικής εταιρείας.

Kύρια  ενδιαφέροντα του είναι η παρακολούθηση  των ασθενών με οισοφάγο Barrett’s και ελκώδη κολίτιδα καθώς και η ενδοσκοπική μελέτη ασθενών με προκαρκινικές αλλοιώσεις στο πεπτικό [δυσπλασία]. Στη θεραπευτική ενδοσκόπηση κύριο ενδιαφέρον του είναι οι σύνθετες πολυποδεκτομές επίπεδων πολυπόδων [ενδοσκοπική βλεννογονεκτομή] και η καταστροφή του επιθηλίου του οισοφάγου Barrett με radiofrequency ablation [HALO].

Είναι ομιλητής σε πολλά ελληνικά και διεθνή συνέδρια ενώ έχει επιδείξει ζωντανά τις προηγμένες ενδοσκοπικές αυτές τεχνικές σε ενδοσκοπικά σεμινάρια τόσο στην Ελλάδα όσο και στο εξωτερικό. Μεγάλος αριθμός των εργασιών του είναι δημοσιευμένες σε έγκριτα peer-reviewed ιατρικά περιοδικά στο εξωτερικό, ενώ έχει περισσότερες από 100 δημοσιεύσεις σε ελληνικά και ξένα συνέδρια. Αρθρογραφεί συχνά στον ελληνικό τύπο.

Διατηρεί ιατρείο στην οδό Βασιλίσσης Σοφίας 82, Αθήνα [τηλ 210 7716420, 6937106139]

E-mail gkanagnostopoulos@yahoo.gr

Website www.gastrohep.gr

 

Date of Birth 19/03/1970

Nationality Greek

GMC Full registrationReference Number 4497642

Driving Licence Full clean Licence (EEC)

Marital Status Married with one daughter

QUALIFICATION

Ptychio Iatrikes – Equivalent to MB BS (Distinction) 1994

FOREIGN LANGUAGE KNOWLEDGE

English: fluently Cambridge University Proficiency Certificate in English (December 1984)

Michigan University Proficiency Certificate in English (February 1985)

German Grundstufe sprachdiplom (1989)

Greek: native language

PRESENT APPOINTMENT [ 3/06 – present]

• Consultant Gastroendoscopist, Endoscopy Department, Mitera General Hospital, Athens, Greece
• Consultant Gastroendoscopist, Second Gastroenterology Clinic, Evangelismos Hospital Athens Greece
• Director of Endoscopy Dpt, Therapeftirio Kypselis, Athens, Greece

PREVIOUS APPOINTMENTS

03.02.06 – 27.03.06 Advanced Endoscopy Fellow, Endoscopy Department, University of Mainz, Germany

Pr Ralf Kiesslich

15.05.2004 – 03.02-2006 Advanced Endoscopy Fellow, Wolfson Digestive Diseases Centre, University Hospital, Queen’s Medical Centre, Nottingham, UK

Pr CJ Hawkey, Pr K Ragunath

13.03.2002- 12.03.2007 Honorary Research Fellow, Gastroenterology Department, University of Ioannina, Greece

December 1999 – December 2003 Gastroenterology SpR in the 251 Hellenic Air Force and Veterans General Hospital of Athens.

Supervising Consultants: Colonell Dr D Arvanitidis, Colonell Dr P Kostopoulos

September 1998 – September 1999 Senior House Officer in Internal Medicine in the ‘Elpis’ General Hospital, Athens, Greece

Supervising Consultant: Dr P Skliros, Dr E Lambrou

August 1996 – September 1998 Rural Doctor on Ios island, Kyklades, Greece

March 1995 – June 1996 Senior House Officer in Internal Medicine in the ‘Naval and Veterans General Hospital of Athens’, Athens, Greece

Supervising Consultant: Dr D Kotilis

MEDICAL SCHOOL 

Medical School National Kapodistrian University of Athens Medical school, Greece

Ptychio Iatrikes – Equivalent to MB BS Distinction

Grammar School Protypon (Model) High School of Anavryta, Athens, Greece. Annual Distinctions (1982-1987), and Distinction of best student in class (1985, 1986, 1987)

High School Certificate of Secondary Education Distinction

Military Service (compulsory)-Medical Officer

July 1994 – March 1995 Battleship “Arethousa”

March 1995- June 1996 Naval and Veterans General Hospital of Athens

(total 23 months) Internal Medicine Department

GASTROENTEROLOGY AND GENERAL MEDICINE EXPERIENCE IN GREECE

Clinical Work: I have been trained in Gastroenterology in a busy unit in the 251 Hellenic Air Force and Veterans General Hospital (Consultant Colonel Dr D. Arvanitidis), which serves a population of about 250,000 people. I was a Registrar for 4 years in the hospital taking care of the inpatients in the Gastroenterology ward, and managing emergency gastroenterology-related admissions. I was also working in the gastroenterology and hepatology outpatient department of my unit twice a week with special interest

· on the outpatient follow-up of HCV and HBV patients receiving antiviral treatment, and have performed more than 50 percutaneous liver biopsies.

· on the treatment and follow up of patients with Inflammatory Bowel Disease

During my training I was participating in the Gastrointestinal Rota of the Hospital for Upper GI bleeding , and was also participating in the on-call rota which was 1 every 3 days. I was organising the journal club of my unit with case presentations and literature review.

I was also participating in the Multihospital journal club of Athens which is organised yearly and consists of lectures and case presentations from SpRs from Greek hospitals.

During my training I performed more than 2500 endoscopic procedures in total including, apart from diagnostic upper and lower GI endoscopies, placement of Percutaneous Endoscopic Gastrostomies, stricture dilatation, polypectomies, haemostatic procedures in both upper/lower GI, foreign body removal, and intraoperative endoscopy.

As an SHO I worked two years in the Internal Medicine Departments of the Naval and Veterans General Hospital of Athens (Consultant Dr D. Kotilis), and “Elpis” General Hospital of Athens (Consultant Dr P. Skliros) dealing with multispeciality patients and participating in the ward-round, outpatient and emergency Department. I also worked as the only rural general doctor on Ios island for two years serving a population of 2,000 people on winter and about 60,000 people during summertime.

Teaching: During my Internal Medicine appointments I was involved in the teaching of Physical Examination in students of the Medical School. During my Gastroenterology appointment, I was involved in the teaching of acute Gastroenterology in Military doctors and was also giving often lectures to the Military Nursing stuff of the hospital.

Research: During my appointment as a Gastroenterology Registar I was involved in the Research activities of the Department and was the lead investigator in the 3 clinical trials which were conducted and the results have already been published in peer-reviewed journals and presented in international congresses. Since March 2003 I have been working on my PhD research project in the University of Ioannina, Medical School. We have performed an immunohistochemical analysis of the carcinogenesis pathway in human stomach, detecting several proteins regulating apoptosis and cell proliferation in gastric biopsies samples of patients with atrophic gastritis, enteric metaplasia, gastric dysplasia and gastric adenocarcinoma (cyclin D1, cyclin E, cyclin D3, bax, bcl-2, caspase-8, caspase-9, ki-67, p27/kip1, p53). The experimental part of the project has finished and I am at the moment writing up my thesis. The project involves 200 patients and is supervised by:

1) N. Agnantis MD, PhD. Professor of Pathology, University of Ioannina Medical School and

2) E. Tsianos MD, PhD. Professor of Gatroenterology, University of Ioannina, Medical School.

General: Besides my clinical skills, I developed my communication and interpersonal skills. I have good working relationships with my colleagues and I also have the ability to communicate effectively with patients and their relatives. I have also developed my IT skills and I can comfortably use Word, Excel and Powerpoint. I can also access the major on-line medical databases and I daily use e-mail and the Internet. 

CCST EXAMS

On February 2004 I passed the oral, written and endoscopic CCST Greek exams, and since April 2004 I am a specialist Gastroenterologist in Greece. Since 2010 I am also eligible for the European diploma of Gastroentrology.

EXPERIENCE IN THE UNITED KINGDOM

Advanced Endoscopy Research Fellow

Wolfson Digestive Diseases Centre

University Hospital

Queen’s Medical Centre

Nottingham

UK

Research: I was participating with Dr Krish Ragunath, and Professor Kenshi Yao, Fukuoka, University Hospital, in a research programme focussing on advanced endoscopic imaging, using novel optical techniques. This included, chromoendoscopy, magnification endoscopy, high resolution / high definition endoscopy, Autofluoresence endoscopy and Narrow Band Imaging. A clinical research programme was established to conduct multi-centre trials with Academic Medical Centre, Amsterdam and Mayo Clinic, USA. We also established collaboration with Dr Steve Morgan, Dept. of Engineering and Electronics to develop a fibre based Endoscopic Hyperspectral Imaging to detect early cancer changes in the gut mucosa. We were collaborating with Prof Sue Watson in the department of pre-clinical oncology to investigate the role of Gastrin and other biomarkers in Barrett’s oesophagus.

Teaching: I was regularly teaching (clinical bed side and lecture) medical students attached to our unit. I gave lectures to the endoscopy users group meeting which has been initiated and organised by Dr Ragunath to discuss endoscopy related literature and training.

Academic and Scholarly activity: Other than research and teaching, I regularly participated in the weekly journal clubs, clinical meetings including X-ray, histopathology and cancer multi-disciplinary team meetings. Reviewing manuscripts for journals is particularly interesting and I regularly review for Digestive Diseases & Sciences, Clinical Gastroenterology and Hepatology, and World Journal of Surgical Oncology on endoscopy related topics and luminal gastroenterology.

Clinical work: My commitments to the post involved 4 clinical sessions directly involving patient care (4 endoscopy, 1 clinic, on call rota for emergency endoscopy). I perform a full range of diagnostic and therapeutic GI endoscopy procedures including gastroscopy, colonoscopy, and I have been trained in ERCP. I also participated in the 1:8 Endoscopy bleeding rota.

Endoscopy Skills

• I have independently performed over 5000 upper GI endoscopies including; oesophageal dilatation, insertion of oesophageal metal stents, variceal injection / banding / haemoclip / thermal ablation of bleeding gastric / duodenal ulcer and percutaneous endoscopic gastrostomy (PEG) procedures.

• I have independently performed over 6000 colonoscopies including hot biopsy and snare polypectomies, EMR, colonic stent placement

• I have been trained and currently perform radiofrequency ablation of Barrett’s epithelium with the HALO system [Barrx]

• Intragastric balloon placement for morbid obesity

• I have performed over 400 diagnostic and therapeutic ERCPs.

Additional (advanced) Endoscopy skills

• High resolution magnification, chromoendoscopy, Narrow Band Imaging and confocal endomicroscopy : These are my major area of interest and have expertise in this new exciting technology to image the GI tract.

• Endoscopic thermal treatment: I am trained in the principles and practice of Argon Plasma Coagulation.

• GI luminal stenting: I have good experience in oesophageal/gastric outlet / duodenal/colonic stent insertion.

• Endoclip application: I am trained in the use of endoscopic metal clip application for haemostasis and closure of perforation in the GI tract.

• Therapeutic ERCP: I have been trained in biliary therapeutic procedures including sphincterotomy, stone extraction, plastic and metal biliary stent insertion. I have limited experience in Sphincter of Oddi manometry, pancreatic endotherapy, endoscopic pseudo-cyst drainage and endoscopic ampullectomy for ampullary tumours.

• Endoscopic Mucosal Resection (EMR): I have gained extensive knowledge of the technique, principles and practice of EMR with some experience in oesophago-colonic EMR.

Research Experience

During my recent post in UK, I was involved in several research projects. I was the lead investigator in the following projects:

• Tissue effects of methylene blue chromoendoscopy in Barrett’s oesophagus. George K Anagnostopoulos, P Fortun, J Smith, K Ragunath.

• Liquid Cytology, Brush Flow Cytometry and Fluorescence In Situ Hybridization (FISH) Flow Cytometry in Barrett’s Oesophagus. George K Anagnostopoulos, Paul Fortun, Krish Ragunath, P Kaye.

• High resolution magnification endoscopy can identify Helicobacter pylori infection, gastric atrophy and gastric intestinal metaplasia. George K Anagnostopoulos, Krish Ragunath, Kenshi Yao, John Atherton.

• High resolution magnification endoscopy with Narrow Band imaging in Barrett’s oesophagus. George K Anagnostopoulos, Krish Ragunath, Kenshi Yao, Christopher J Hawkey.

I was also co-investigator in the following projects:

• The effect of proton pump inhibitor therapy on gastrin, gastrin gene, gastrin/ CCK-2 receptor, protein kinase-B/Akt (total and activated) and XIAP expression in biopsy samples from patients with Barrett’s Oesophagus. Arjun S Takhar, Joseph Harris, Krish Ragunath, George Anagnostopoulos, Susan Watson 

• Natural history of low and high grade dysplasia in Barrett’s oesophagus. Results from the Nottingham database in a period of 20 years.

Faisek W, George K Anagnostopoulos, Krish Ragunath, Kenshi Yao, Christopher J Hawkey.

• Acetic acid enhanced magnification endoscopy to diagnose specialist intestinal metaplasia, dysplasia and early cancer in Barett’s oesophagus. Fortun P, Anagnostopoulos GK, Kaye P, James M, Folley S, Samuel S, Balderldin R, Campbell E, Hawkey CJ, Ragunath K.

Prizes

1. Medical School Distinction 1994

2. High School Distinction 1987 (yearly distinctions from 1982-1987, and distinction in 1985, 1986, and 1987 as best student in class)

3. 3^rd prize for best oral presentation in 23^rd Panhellenic Congress of Gastroenterology [2003]

4. 1^st prize for best poster presentation in the 1^st congress of the Greek society of GI surgery [2003]

5. Annual scholarship from the Hellenic Gastroenterology Association (2004-2005), to work as an advanced endoscopy Fellow in WDDC, University of Nottingham, UK.

6. Olympus Keymed prize 2005 to attend the Beach Congress in MUSC with Pr Peter Cotton.

7. 1^St Prize for best oral presentation in 27^rd Panhellenic Congress of Gastroenterology [2007]

PUBLICATIONS IN FOREIGN PEER-REVIEWED JOURNALS (INDEXED IN PUBMED)

1. Early (mucosal) gastric cancer with synchronous osteosclerotic bone metastases: a case report. Anagnostopoulos G, Sakorafas GH, Kostopoulos P, Margantinis G, Tsiakos S, Pavlakis G. Eur J Cancer Care (Engl). 2009 Aug 26

2. Intestinal neurofibromatosis and small-bowel adenocarcinoma: a single case study.

Stratopoulos C, Papakonstantinou A, Anagnostopoulos G, Terzis I, Tzimas G, Gourgiotis S, Vamvouka C, Hadjiyannakis E. Eur J Cancer Care (Engl). 2009 Sep;18(5):466-9

3. Magnifying endoscopy for diagnosing and delineating early gastric cancer. Yao K, Anagnostopoulos GK, Ragunath K. Endoscopy. 2009 May;41(5):462-7.

4. Yao K, Takaki Y, Matsui T, Iwashita A, Anagnostopoulos GK, Kaye P, Ragunath

K. Clinical application of magnification endoscopy and narrow-band imaging in the upper gastrointestinal tract: new imaging techniques for detecting and characterizing gastrointestinal neoplasia. Gastrointest Endosc Clin N Am. 2008;18:415-33

5. Singh R, Yao K, Anagnostopoulos G, Kaye P, Ragunath K. Microcarcinoid tumor diagnosed with high-resolution magnification endoscopy and narrow band imaging. Endoscopy. 2008 Feb 18; [Epub ahead of print]

6. Anagnostopoulos GK, Stefanou D, Arkoumani E, Chalkley L, Karagiannis J, Paraskeva K, Mathou N, Dellaporta E, Tsianos E, Agnantis NJ. Expression of Bax protein in gastric carcinomas. A clinicopathological and immunohistochemical study.Acta Gastroenterol Belg. 2007 Jul-Sep;70(3):285-9.

7. Anagnostopoulos GK, Yao K, Kaye P, Hawkey CJ, Ragunath K. Novel endoscopic observation in Barrett’s oesophagus using high resolution magnification endoscopy and narrow band imaging. Aliment Pharmacol Ther. 2007 Aug 1;26(3):501-7

8. Aithal GP, Anagnostopoulos GK, Tam W, Dean J, Zaitoun A, Kocjan G, Ragunath K, Pereira SP. EUS-guided tissue sampling: comparison of “dual sampling” (Trucut biopsy plus FNA) with “sequential sampling” (Trucut biopsy and then FNA as required). Endoscopy. 2007 Aug;39(8):725-30. Epub 2007 Jul 10.

9. Anagnostopoulos GK. Magnification endoscopy with acetic acid in Barrett’s esophagus. Scand J Gastroenterol. 2007 Apr;42(4):542

10. Anagnostopoulos GK, Yao K, Kaye P, Fogden E, Fortun P, Shonde A, Foley S, Sunil S, Atherton JJ, Hawkey C, Ragunath K.High-resolution magnification endoscopy can reliably identify normal gastric mucosa, Helicobacter pylori-associated gastritis, and gastric atrophy.Endoscopy. 2007 Mar;39(3):202-7. Epub 2007 Feb 1.

11. Anagnostopoulos GK, Margantinis G, Tsiakos S, Kostopoulos P, Grigoriadis K, Arvanitidis D. Postinfantile giant-cell hepatitis associated with ulcerative colitis and autoimmune hepatitis. J Gastroenterol Hepatol. 2006 Dec;21(12):1863-4

12. Stratopoulos C, Pitsios C, Valenti P, Anagnostopoulos G, Kotronis E. Medical Image. Deep vein thrombosis due to absence of inferior vena cava.
    N Z Med J. 2006 Oct 27;119(1244):U2288

13. Ragunath K, Anagnostopoulos GK, Dunn K. Education and imaging. Hepatobiliary and pancreatic: Choledochopancreatic fistula complicating acute pancreatitis. J Gastroenterol Hepatol. 2006 Nov;21(11):1753.

14. Anagnostopoulos GK, Shonde T, Kaye P, Ragunath K. A case of a “fragile” oesophagus. Gut. 2006 Oct;55(10):1495.

15. Yao K, Anagnostopoulos GK, Sou S, Nagahama T, Iwashita A, Matsui T.Minimum required resolution standard required for analysis of mucosal microvascular architecture at magnification endoscopy. Endoscopy. 2006 Jul;38(7):757

16. Anagnostopoulos GK, Ragunath K, Shonde A, Hawkey CJ, Yao K. Diagnosis of autoimmune gastritis by high resolution magnification endoscopy. World J Gastroenterol. 2006 Jul 28;12(28):4586-7

17. Vlachou PA, Aslam M, Murphy P, Ntatsios A, Anagnostopoulos GK. Non-surgical pneumoperitoneum following cervical smear test. Eur J Obstet Gynecol Reprod Biol. 2006 Jun 13

18. Anagnostopoulos GK, Pick B, Cunliffe R, Fortun P, Kaye P, Ragunath K. Barrett’s esophagus specialist clinic: what difference can it make? Dis Esophagus. 2006;19(2):84-7

19. Fortun PJ, Anagnostopoulos GK, Kaye P, James M, Foley S, Samuel S, Shonde A, Badreldin R, Campbell E, Hawkey CJ, Ragunath K. Acetic acid-enhanced magnification endoscopy in the diagnosis of specialized intestinal metaplasia, dysplasia and early cancer in Barrett’soesophagus. Aliment Pharmacol Ther. 2006 Mar 15;23(6):735-42.

20. Anagnostopoulos GK, Aithal GP, Ragunath K, Kaye P, Rowlands BJ. Squamous cell carcinoma of the pancreas: report of a case and review of the literature. JOP. 2006 Jan 11;7(1):47-50.

21. Anagnostopoulos G, Foley S, Ragunath K.Dieulafoy lesion in the duodenum. N Z Med J. 2005 Nov 11;118(1225):U1730.

22. Anagnostopoulos GK, Stefanou D, Arkoumani E, Arvanitidis D, Sakorafas G, Pavlakis G, Tsianos E, Agnantis NJ. Bax and bcl-2 protein expression in gastric precancerous lesions. An immunohistochemical study. J Gastroenterol Hepatol. 2005 Nov;20(11):1674-

23. Aithal GP, Anagnostopoulos GK, Kaye P. EUS-guided Trucut mural biopsies in the investigation of unexplained thickening of the esophagogastric wall. Gastrointest Endosc. 2005 Oct;62(4):624-9

24. Kolilekas L, Gallis P, Liasis N, Anagnostopoulos GK, Eleftheriadis I. Unusual Case of Pulmonary Hypertension. Respiration. 2005 Jul 21; [Epub ahead of print]

25. Anagnostopoulos GK, Ragunath K, Fortun PJ, Yao K. Identifying Helicobacter pylori-associated gastritis, gastric atrophy and intestinal metaplasia with magnification endoscopy and adaptive index of haemoglobin enhancement technique. Dig Liver Dis. 2005 Dec;37(12):980-1

26. Anagnostopoulos GK, Fortun P, Ragunath K, Hawkey CJ. Images of interest. Gastrointestinal: early endoscopic findings in watermelon stomach identified by the magnifying endoscopy-adaptive IHb color enhancement technique. J Gastroenterol Hepatol. 2005 Jul;20(7):1122.

27. Fortun P, Anagnostopoulos G, Laurence B. Suture material as a nidus for common bile duct stones: taking a closer look. N Z Med J. 2005 Feb 25;118(1210):U1318.

28. Sakorafas G, Anagnostopoulos G, Stafyla V, Koletis T, Kotsifopoulos N, Tsiakos S, Kassaras G. Elevation of serum liver enzymes after laparoscopic cholecystectomy. N Z Med J. 2005 Feb 25;118(1210):U1317.

29. Tslotou AG, Sakorafas GH, Anagnostopoulos G, Bramis J. Septic shock; current pathogenetic concepts from a clinical perspective. Med Sci Monit. 2005 Mar;11(3):RA76-85. Review.

30. Anagnostopoulos G, Sakorafas GH, Grigoriadis K, Margantinis G, Kostopoulos P, Tsiakos S, Arvanitidis D. Hepatitis caused by occupational chronic exposure to trichloroethylene. Acta Gastroenterol Belg. 2004 Oct-Dec;67(4):355-7.

31. Anagnostopoulos GK, Sakorafas GH, Kostopoulos P, Margantinis G, Tsiakos S, Terpos E, Pavlakis G, Fortun P, Arvanitidis D. Disseminated colon cancer with severe peripheral blood eosinophilia and elevated serum levels of interleukine-2, interleukine-3, interleukine-5, and GM-CSF. J Surg Oncol. 2005 Mar 15;89(4):273-5.

32. Anagnostopoulos G, Sakorafas GH, Kostopoulos P, Grigoriadis K, Pavlakis G, Margantinis G, Vugiouklakis D, Arvanitidis D. Squamous cell carcinoma of the rectum: a case report and review of the literature. Eur J Cancer Care (Engl). 2005 Mar;14(1):70-4.

33. Anagnostopoulos G, Sakorafas GH, Grigoriadis K, Kostopoulos P. Malignant fibrous histiocytoma of the liver: a case report and review of the literature. Mt Sinai J Med. 2005 Jan;72(1):50-2.

34. Bays D, Anagnostopoulos GK, Katsaounos E, Filis P, Missas S. Inflammatory fibroid polyp of the small intestine causing intussusception: a report of two cases. Dig Dis Sci. 2004 Oct;49(10):1677-80.

35. Anagnostopoulos GK, Doriforou O, Sakorafas G, Missas S. Tuberous sclerosis associated with giant bilateral bleeding angiomyolipomas. Postgrad Med J. 2004 Oct;80(948):580.

36. Pavlakis G, Sakorafas GH, Anagnostopoulos GK, Grigoriadis K, Symeonidis G. Lateral cervical cyst with unsuspected metastasis from an occult tonsillar carcinoma. J Postgrad Med. 2004 Jul-Sep;50(3):202-4.

37. Arvanitidis D, Anagnostopoulos GK, Tsiakos S, Margantinis G, Kostopoulos P. Cholecystocolic fistula demonstrated by endoscopic retrograde cholangiopancreatography. Postgrad Med J. 2004 Sep;80(947):526.

38. Kolilekas L, Anagnostopoulos GK, Lampaditis I, Eleftheriadis I. Potential interaction between telithromycin and warfarin. Ann Pharmacother. 2004 Sep;38(9):1424-7. Epub 2004 Jul 27.

39. Anagnostopoulos GK, Margantinis G, Kostopoulos P, Papadopoulou G, Roulias A, Sakorafas G, Liassis N. Budd-Chiari syndrome and portal vein thrombosis due to right atrial myxoma. Ann Thorac Surg. 2004 Jul;78(1):333-4.

40. Anagnostopoulos GK, Tsiakos S, Margantinis G, Kostopoulos P, Arvanitidis D. Esomeprazole versus omeprazole for the eradication of Helicobacter pylori infection: results of a randomized controlled study. J Clin Gastroenterol. 2004 Jul;38(6):503-6.

41. Anagnostopoulos GK, Sakorafas G, Kolettis T, Kotsifopoulos N, Kassaras G.A case of gallstone ileus with an unusual impaction site and spontaneous evacuation. J Postgrad Med. 2004 Jan-Mar;50(1):55-6.

42. Sakorafas GH, Vlachos A, Tolumis G, Kassaras GA, Anagnostopoulos GK, Gorgogiannis D. Ectopic intrathoracic thyroid: case report. Mt Sinai J Med. 2004 Mar;71(2):131-3

43. Pavlakis GM, Sakorafas GH, Anagnostopoulos GK. Intestinal metastases from renal cell carcinoma: a rare cause of intestinal obstruction and bleeding. Mt Sinai J Med. 2004 Mar;71(2):127-30.

44. Anagnostopoulos GK, Arvanitidis D, Sakorafas G, Pavlakis G, Kolilekas L, Arkoumani E, Stefanou D. Combined carcinoid-adenocarcinoma tumour of the anal canal. Scand J Gastroenterol. 2004 Feb;39(2):198-203

45. Arvanitidis D, Anagnostopoulos GK, Giannopoulos D, Pantes A, Agaritsi R, Margantinis G, Tsiakos S, Sakorafas G, Kostopoulos P. Can somatostatin prevent post-ERCP pancreatitis? Results of a randomized controlled trial. J Gastroenterol Hepatol. 2004 Mar;19(3):278-82.

46. Anagnostopoulos GK, Margantinis G, Tsiakos S, Kostopoulos P, Arvanitidis D. Liver cirrhosis observed in a patient with chronic excessive menthol intake. J Gastroenterol Hepatol. 2004 Feb;19(2):239-40.

47. Sakorafas GH, Anagnostopoulos G. Surgical management of chronic pancreatitis: current concepts and future perspectives. Int Surg. 2003 Oct-Dec;88(4):211-8.

48. Anagnostopoulos GK, Kostopoulos P, Arvanitidis DM. Buried bumper syndrome with a fatal outcome, presenting early as gastrointestinal bleeding after percutaneous endoscopic gastrostomy placement. J Postgrad Med. 2003 Oct-Dec;49(4):325-7.

49. Anagnostopoulos G, Margantinis G, Tsiakos S, Kostopoulos P, Pantes A, Arvanitidis D. Myopericarditis associated with ulcerative colitis. N Z Med J. 2003 Nov 7;116(1185):U667

50. Anagnostopoulos GK, Kostopoulos P, Tsiakos S, Margantinis G, Arvanitidis D. Fulminant pancreatitis associated with ramipril therapy. Pancreas. 2003 Oct;27(3):278-9.

51. Anagnostopoulos GK, Arvanitidis D, Tsiakos S, Margantinis G, Grigoriadis K, Kostopoulos P. Is hepatocellular carcinoma part of the natural history of nonalcoholic steatohepatitis? J Clin Gastroenterol. 2003 Jul;37(1):88-9

52. Anagnostopoulos GK, Tsiakos S, Margantinis G, Kostopoulos P, Arvanitidis D. Acute pancreatitis due to pravastatin therapy. JOP. 2003 May;4(3):129-32.

53. Anagnostopoulos GK, Kostopoulos P, Margantinis G, Tsiakos S, Arvanitidis D. Omeprazole plus azithromycin and either amoxicillin or tinidazole for eradication of Helicobacter pylori infection. J Clin Gastroenterol. 2003 Apr;36(4):325-8.

54. P27 and gastric carcinoma. A review. George K Anagnostopoulos, D.Stefanou, Niki J Agnantis. Gastric Breast Cancer 2005

MANUSCRIPTS UNDER PREPARATION FOR SUBMISSION

· Fasek W, Anagnostopoulos GK, Kaye P, Yao K, Ragunath K. The natural history of low and high grade dysplasia in Barrett’s oesophagus. A retrospective study from the Nottingham database between 1983-2005.

· Anagnostopoulos GK, Smith J, Ragunath K, Hawkey CJ. Reversibility of DNA damage caused by methylene blue in human oesophagus and oesophageal cell lines.

· Anagnostopoulos GK, Ragunath K, Ryder S, Aithal GP. Safety and efficacy of ERCP in patients older than 85 years old.

· Anagnostopoulos GK, Kaye P, Ragunath K, Yao K, Hawkey CJ. Liquid cytology, flow cytometry and FISH-Flow in neoplastic and non-neoplastic Barrett’s epithelium. A pilot study

· Anagnostopoulos GK, Canto M, Goetz M, Hoffmann A, Kiesslich R. Inter and intraobserver variability study in the assessment of Confocal endomicroscopy images.

· Anagnostopoulos GK, Georgiadis D, Viazis N, Karamanolis D. Identification of flat colonic polyps with panchromoendoscopy with acetic acid in a Western population. A validation study

· Anagnostopoulos GK, Georgiadis D, Viazis N, Karamanolis D. Identification of flat colonic polyps with panchromoendoscopy with acetic acid/indigo carmine in a Western population. A validation study

· Anagnostopoulos GK, Georgiadis D, Viazis N, Karamanolis D. Magnification endoscopy with NBI in the cardia shows a high incidence of intestinal metaplasia which has the same microstructural and microvascular patterns with Barrett’s esophagus 

Member of the Editorial Board

World journal of Gastrointestinal Endoscopy since 2009

Annals of Gastroenterology – Section Editor since 2010

LIVE DEMONSTRATION OF ADVANCED ENDOSCOPIC IMAGING TECHNIQUES

· Panhellenic Congress of Gastroenterology, 2007

· Panhellenic Congress of Gastroenterology, 2006

· Panhellenic Congress of Gastroenterology 2005

· Εndoscopy Live Athens, 2006

· Evangelismos endoscopy day, 2007

· 1^st advanced endoscopy European symposium, Nottingham 2006

· 2^nd advanced endoscopy European symposium, Nottingham 2007

· Μidlands endoscopy symposium, Scheffield 2006

WEB PUBLICATIONS

Case of the month. Pits Pitfalls and Polyps. George K Anagnostopoulos.

Published online at the Website of British Society of Gastroenterology December 2004

PRESENTATIONS IN NATIONAL AND INTERNATIONAL CONGRESSES

· Enhanced magnification endoscopy in Barrett’s oesophagus.

Fortun P, Anagnostopoulos GK, Kaye P, Hawkey CJ, Ragunath K, Wolfson Digestive Diseases Centre and Dept. of Pathology, University Hospital Nottingham, UK

Oral presentation at the BSG meeting, Birmingham, March’05. Gut (Suppl II) April 2005;54;A12. Oral presentation at the DDW, Chicago May’05. Gastrointest Endosc April 2005;61:AB104.

· A novel technique of endoscopic ultrasound guided trucut mural biopsies in the investigation of unexplained thickening of oesophageal wall.

Anagnostopoulos G, Zaitoun A, Kaye P, Ragunath K, Aithal GP. Wolfson Digestive Diseases Centre and Dept. of Pathology, University Hospital Nottingham, UK.

Oral presentation at the BSG meeting, Birmingham, March’05. Gut (Suppl II) April 2005;54;A16.

· Impact of a specialist clinic in the management of patients with Barrett’s oesophagus.

Anagnostopoulos G, Pick B, Ragunath K. Wolfson Digestive Diseases Centre, University Hospital Nottingham, UK

Poster presentation at the BSG meeting, Birmingham, March’05. Gut (Suppl II) April 2005;54;A108.

· High resolution magnification endoscopy with adaptive index of haemoglobin colour enhancement to evaluate the UGI tract.

Ragunath K, Anagnostopoulos G, Fortun P, Kay P, Hawkey CJ. Wolfson Digestive Diseases Centre and Dept. of Pathology, University Hospital Nottingham, UK

Poster presentation at the BSG meeting, Birmingham, March’05. Gut (Suppl II) April 2005;54;A65. Poster presentation at the DDW Chicago May’05. Gastrointest Endosc April 2005;61:AB236.

· Inter and Intra observer consistency in recognizing pit patterns in Barrett’s esophagus using the enhanced magnification endoscopy technique. Anagnostopoulos GK, Ragunath K, Fortun PJ, James M, Folley S, Samuel S, Shonde A, Badreldin R, Campbell E, Hawkey CJ. Poster presentation at the DDW, Chicago May’05. Gastrointest Endosc April 2005;61:AB126.

· A novel technique of Endoscopic ultrasound (EUS) guided Trucut mural biopsies in the investigation of unexplained thickening of oesophagogastric wall. Anagnostopoulos GK, Kaye P,Aithal GP. Annual meeting of the British Society of Gastroenterology Meeting, Birmingham 14-17 March 2005 Gut, Apr 2005;54: a1 – a117.

· P27 in gastric carcinogenesis and its prognostic role in gastric cancer. George K Anagnostopoulos, D Stefanou, E Arkoumani, E Tsianos, NJ Agnantis.British Society of Gastroenterology Scientific Meeting 14-17 March 2005. Gut, Apr 2005;54: a1 – a117.

· Immunohistochemical expression on cell cycle proteins in gastric precancerous lesions. GK Anagnostopoulos, D Stefanou, E Arkoumani, K Paraskeva, E Tsianos, NJ Agnantis 12th United European Gastroenterology Week Prague 09/2004

· Bax/Bcl-2 protein expression in gastric precancerous lesions: an immunohistochemical study. George K Anagnostopoulos, D Stefanou, E Arkoumani, D Arvanitidis, G Sakorafas, G Pavlakis, E Tsianos, NJ Agnantis11^th United European Gastroenterology Week, Madrid 11/2003.

· Coeliac Disease.Annual meeting of the Hellenic Gastroenterological society 2001

· HCV infection: guidelines in management. Multispecialist congress of Air Force Hospital, 2002

· Omeprazole plus azithromycin and either tinidazole or amoxycillin for eradication of Helicobacter pylori infection.G. Anagnostopoulos, P. Kostopoulos, S. Tsiakos, G. Margantinis, D. ArvanitidisEuropean Congress of Helicobacter study group, Athens, 09/2002

· The role of somatostatin in the prevention of post-ERCP pancreatitis and hyperamylasemia: a randomized controlled trialD. Arvanitidis, G. Anagnostopoulos, P. Kostopoulos, S. Tsiakos, G. Margantinis.Panhellenic Congress of Gastroenterology, Athens, 11/2002

• Natural history of dysplasia in Barrett’s oesophagus (BE). Faisal W, Anagnostopoulos G, Kaye P, Logan R, Ragunath K. Wolfson Digestive Disease Centre, University Hospital Nottingham, UK. Annual meeting of the British Society of Gastroenterology, Birmingham, March 2006.

• Comparison of diagnostic yield between biliary brushings & biliary biopsy: results of a pilot study. Ali F, Richards D, Anagnostopoulos G, Zaitoun A, Griffiths P, Tofazzal N, Ragunath K, Aithal G. Annual meeting of the British Society of Gastroenterology, Birmingham, March 2006

• Optical microangiography: high-definition zoom colonoscopy with narrow-band imaging (NBI) technique for visualizing mucosal capillaries and red blood cells (RBC) in the large intestine. Yao K, Anagnostopoulos GK, Jawhari AU, Kaye P, Hawkey CJ, Ragunath K. Annual meeting of the British Society of Gastroenterology, Birmingham, March 2006

• Detection of Helicobacter pylori (HP) gastritis and gastric atrophy by real time high resolution magnification endoscopy (HRME). Anagnostopoulos GK,Yao K, Hawkey CJ, Ragunath K. Annual meeting of the British Society of Gastroenterology, Birmingham, March 2006

• High resolution magnification endoscopy (HRME) with narrow band imaging (NBI) in patients with Barrett’s oesophagus. Anagnostopoulos GK, Yao K, Hawkey CJ, Ragunath K. Annual meeting of the British Society of Gastroenterology, Birmingham, March 2006

• Bax protein expression in gastric cancer: a clinicopathological and immunohistochemical study. Anagnostopoulos GK, Stefanou D, Arkoumani E,Tsianos E, Agnantis NJ. Annual meeting of the British Society of Gastroenterology, Birmingham, March 2006

• Confocal microscopy: a novel method to assess aberrant crypt foci in APCmin+/- and APCmin+/- (PPARα-/-) mice. Shonde A, Ragunath K, Anagnostopoulos G, Bell DR, Bennett AJ, Hawkey CJ. Annual meeting of the British Society of Gastroenterology, Birmingham, March 2006

• Confocal microscopy: a novel method to assess aberrant crypt foci in APCmin+/- and APCmin+/- (PPARα-/-) mice. Shonde A, Ragunath K, Anagnostopoulos G, Bell DR, Bennett AJ, Hawkey CJ. DDW 2006

• High resolution magnification endoscopy (HRME) with narrow band imaging (NBI) in patients with Barrett’s oesophagus. Anagnostopoulos GK, Yao K, Hawkey CJ, Ragunath K. DDW 2006

• Optical microangiography: high-definition zoom colonoscopy with narrow-band imaging (NBI) technique for visualizing mucosal capillaries and red blood cells (RBC) in the large intestine. Yao K, Anagnostopoulos GK, Jawhari AU, Kaye P, Hawkey CJ, Ragunath K. DDW 2006

• Detection of Helicobacter pylori (HP) gastritis and gastric atrophy by real time high resolution magnification endoscopy (HRME). Anagnostopoulos GK,Yao K, Hawkey CJ, Ragunath K. DDW 2006

• High resolution magnification endoscopy can reliably identify the normal gastric mucosa, HP infected stomach and gastric atrophy. Anagnostopoulos G.K., Yao K., Kaye P., Fortun P., Fogden E., Shonde A., Folley S., Sunil S., Atherton J., Hawkey C., Ragunath K UEGW 2006

• Shonde, A., Ragunath, K., Anagnostopoulos, G., & Hawkey, C. J. (2006). Cellvizio® system: A Potential advance in confocal endomicroscopy in the diagnosis of gastrointestinal (GI) diseases. UEGW 2006

• Shonde, A., Singh, R., Anagnostopoulos, G. K., Kaye, P., Hawkey, C. J., & Ragunath, K. (2007). Fibered Confocal endomicroscopy: A feasibility study to enhance routine endoscopy. DDW07

• Should We Routinely Administer Orally a Mucolytic/Antifoam Solution Prior to Upper Gastrointestinal Endoscopy? Results of a Randomised Controlled Study Georgios K Anagnostopoulos, Panagiotis Kostopoulos, Athanasios Pantes, Ioannis Theodoropoulos, Eleni S. Komninou, Eleni Vienna, Nikos Viazis, John Vlachogiannakos, Constantinos Markoglou, Dimitrios Karamanolis DDW 2007

• Interobserver Variation and Standardized Training for Confocal Laser Endomicroscopy Image Interpretation in the Upper and Lower GI Tract Ralf Kiesslich, Georgios K. Anagnostopoulos, Anthony Axon, Katja Deinert, Horst Neuhaus, Martin Goetz, Emmanuel Coron, Oliver Pech, Michael Vieth, Constantin Schneider, Peter R. Galle, Markus Neurath Gastrointestinal Endoscopy DDW 2007

• Magnification Endoscopy with Narrow Band Imaging in the Cardia Shows a High Prevalence of Intestinal Metaplasia Which Has Identical Microstructural and Microvascular Patterns with Barrett’s Epithelium  Georgios K. Anagnostopoulos, Krish Ragunath, Kenshi Yao, Rajvinder Singh, John A. Karagiannis, Georgia Xabilomati, Dimitrios Karamanolis DDW 2007

• Fibered Confocal Endomicroscopy: A Feasibility Study to Enhance Routine Endoscopy Anthony Shonde, Rajvinder Singh, George K Anagnostopoulos, Philip Kaye, Christopher J. Hawkey, Krish Ragunath DDW 2007

• Endoscopic Diagnosis of Autoimmune Gastritis Is Feasible with High Resolution Magnification Endoscopy Georgios K.Anagnostopoulos , Kenshi Yao, Anthony Shonde, Rajvinder Singh, John A. Karagiannis, Konstantina D. Paraskeva, Erminia Dellaporta, Georgia Xabilomati, Krish Ragunath DDW 2007

• Electronic Chromoendoscopy in Barrett’s Esophagus Using Narrow Band Imaging: A Study to Validate Mucosal Morphology Findings and Inter /Intra Observer Agreement Rajvinder Singh, George K. Anagnostopoulos, Kenshi Yao, Haris Karageorgiou, Paul Fortun, Anthony Shonde, Klara Garsed, Philip Kaye, Christopher J. Hawkey, Krish Ragunath

• Could the addition of NBI to HRME be of additional value in the identification of normal gastric mucosa, gastric atrophy and HP gastritis? GK Anagnostopoulos, E Symvoulakis, D Georgiadis, N Viazis, D Karamanolis, UEGW 2008

• Panchromoendoscopy with acetic acid improves detection and characterization of colonic polyps. GK Anagnostopoulos, E Symvoulakis, D Georgiadis, N Viazis, D Karamanolis UEGW 2008

Audit Projects

· ERCP audit, outcome in elderly patients. University Hospital Nottingham in progress

· Barrett’s oesophagus surveillance endoscopy patient information questionnaire.

· Natural History of Barrett’s oesophagus. Results from the Nottingham database

· Audit on indications and outcome of EUS in Nottingham, QMC.

Society membership

• American Society for Gastrointestinal Endoscopy
• Hellenic Gastroenterology Society
• Hellenic Society for Gastroenterology and Nutrition
• ECCO

Special Interests

· Barrett’s Oesophagus

· Ulcerative colitis

· Dysplasia

· GI Oncology

· Advanced Endoscopic Imaging and Therapeutic Endoscopy

Extra – curricular activities

Sports

I enjoy jogging, playing table tennis, basket ball and physical training.

Travelling

I like visiting other countries and places.

Literature

I enjoy reading social science fiction books, and poetry. I generally believe that by seeing through other people’s eyes, may reveal things we did not know that exist inside us.

Music

I am interested in all kinds of music and I own a big collection of LP’s and CD’s. For two years I was working also on a radio station as a music producer. I am especially interested in world music and I always believed and believe that music is the best way to express our feelings and thoughts.

Referees

The following have kindly agreed to act as my referees:

e-mail:nagnanti@cc.uoi.gr